Okkema Lab publications
Complete publication list and links in MyBibliography
- Kozlova, A.A., M. Lotfi, and P.G. Okkema, Crosstalk with the GAR-3 Receptor Contributes to Feeding Defects in Caenorhabditis elegans eat-2 Mutants. Genetics, 2019. PMID 30898771.
- Okkema, P.G., The Remarkably Diverse Family of T-Box Factors in Caenorhabditis elegans. Curr Top Dev Biol, 2017. 122: p. 27-54. PMID 28057267.
- Huber, P., T. Crum, and P.G. Okkema, Function of the C. elegans T-box factor TBX-2 depends on interaction with the UNC-37/Groucho corepressor. Dev Biol, 2016. 416(1): p. 266-276. PMID 27265867.
- Milton, A.C. and P.G. Okkema, Caenorhabditis elegans TBX-2 Directly Regulates Its Own Expression in a Negative Autoregulatory Loop. G3 (Bethesda), 2015. 5(6): p. 1177-86. PMID 25873636.
- Ramakrishnan, K., P. Ray, and P.G. Okkema, CEH-28 activates dbl-1 expression and TGF-beta signaling in the C. elegans M4 neuron. Dev Biol, 2014. 390(2): p. 149-59. PMID 24690231.
- Ramakrishnan, K. and P.G. Okkema, Regulation of C. elegans neuronal differentiation by the ZEB-family factor ZAG-1 and the NK-2 homeodomain factor CEH-28. PLoS One, 2014. 9(12): p. e113893. PMID 25474681.
- Reinke, V., M. Krause, and P. Okkema, Transcriptional regulation of gene expression in C. elegans. WormBook, 2013: p. 1-34. PMID 23801596.
- Milton, A.C., A.V. Packard, L. Clary, and P.G. Okkema, The NF-Y complex negatively regulates Caenorhabditis elegans tbx-2 expression. Dev Biol, 2013. 382(1): p. 38-47. PMID 23933492.
- Huber, P., T. Crum, L.M. Clary, T. Ronan, A.V. Packard, and P.G. Okkema, Function of the C. elegans T-box factor TBX-2 depends on SUMOylation. Cell Mol Life Sci, 2013. 70(21): p. 4157-68. PMID 23595631.
- 1Miller, R.R. and P.G. Okkema, The Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specification. PLoS Genet, 2011. 7(8): p. e1002210. PMID 21852953.
- Clary, L.M. and P.G. Okkema, The EGR family gene egrh-1 functions non-autonomously in the control of oocyte meiotic maturation and ovulation in C. elegans. Development, 2010. 137(18): p. 3129-37. PMID 20736289.
- Ray, P., R. Schnabel, and P.G. Okkema, Behavioral and synaptic defects in C. elegans lacking the NK-2 homeobox gene ceh-28. Dev Neurobiol, 2008. 68(4): p. 421-33. PMID 18161854.
- Crum, T.L. and P.G. Okkema, SUMOylation-dependent function of a T-box transcriptional repressor in Caenorhabditis elegans. Biochem Soc Trans, 2007. 35(Pt 6): p. 1424-6. PMID 18031237.
- Roy Chowdhuri, S., T. Crum, A. Woollard, S. Aslam, and P.G. Okkema, The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. elegans. Dev Biol, 2006. 295(2): p. 664-77. PMID 16701625.
- Franks, D.M., T. Izumikawa, H. Kitagawa, K. Sugahara, and P.G. Okkema, C. elegans pharyngeal morphogenesis requires both de novo synthesis of pyrimidines and synthesis of heparan sulfate proteoglycans. Dev Biol, 2006. 296(2): p. 409-20. PMID 16828468.
- Okkema, P.G. and M. Krause, Transcriptional regulation. WormBook, 2005: p. 1-40. PMID 18050428.
- Vilimas, T., A. Abraham, and P.G. Okkema, An early pharyngeal muscle enhancer from the Caenorhabditis elegans ceh-22 gene is targeted by the Forkhead factor PHA-4. Dev Biol, 2004. 266(2): p. 388-98. PMID 14738885.
- Fernandez, A.P., J. Gibbons, and P.G. Okkema, C. elegans peb-1 mutants exhibit pleiotropic defects in molting, feeding, and morphology. Dev Biol, 2004. 276(2): p. 352-66. PMID 15581870.
- Beaster-Jones, L. and P.G. Okkema, DNA binding and in vivo function of C.elegans PEB-1 require a conserved FLYWCH motif. J Mol Biol, 2004. 339(4): p. 695-706. PMID 15165844.
- Kalb, J.M., L. Beaster-Jones, A.P. Fernandez, P.G. Okkema, B. Goszczynski, and J.D. McGhee, Interference between the PHA-4 and PEB-1 transcription factors in formation of the Caenorhabditis elegans pharynx. J Mol Biol, 2002. 320(4): p. 697-704. PMID 12095247.
- Thatcher, J.D., A.P. Fernandez, L. Beaster-Jones, C. Haun, and P.G. Okkema, The Caenorhabditis elegans peb-1 gene encodes a novel DNA-binding protein involved in morphogenesis of the pharynx, vulva, and hindgut. Dev Biol, 2001. 229(2): p. 480-93. PMID 11203704.
- Kuchenthal, C.A., W. Chen, and P.G. Okkema, Multiple enhancers contribute to expression of the NK-2 homeobox gene ceh-22 in C. elegans pharyngeal muscle. Genesis, 2001. 31(4): p. 156-66. PMID 11783006.
- Thatcher, J.D., C. Haun, and P.G. Okkema, The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx. Development, 1999. 126(1): p. 97-107. PMID 9834189.
- Kalb, J.M., K.K. Lau, B. Goszczynski, T. Fukushige, D. Moons, P.G. Okkema, and J.D. McGhee, pha-4 is Ce-fkh-1, a fork head/HNF-3alpha,beta,gamma homolog that functions in organogenesis of the C. elegans pharynx. Development, 1998. 125(12): p. 2171-80. PMID 9584117.
- Haun, C., J. Alexander, D.Y. Stainier, and P.G. Okkema, Rescue of Caenorhabditis elegans pharyngeal development by a vertebrate heart specification gene. Proc Natl Acad Sci U S A, 1998. 95(9): p. 5072-5. PMID 9560230.
- Okkema, P.G., E. Ha, C. Haun, W. Chen, and A. Fire, The Caenorhabditis elegans NK-2 homeobox gene ceh-22 activates pharyngeal muscle gene expression in combination with pha-1 and is required for normal pharyngeal development. Development, 1997. 124(20): p. 3965-73. PMID 9374394.
- Okkema, P.G. and A. Fire, The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle. Development, 1994. 120(8): p. 2175-86. PMID 7925019.
- Okkema, P.G., S.W. Harrison, V. Plunger, A. Aryana, and A. Fire, Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans. Genetics, 1993. 135(2): p. 385-404. PMID 8244003.
- Kuwabara, P.E., P.G. Okkema, and J. Kimble, Germ-line regulation of the Caenorhabditis elegans sex-determining gene tra-2. Dev Biol, 1998. 204(1): p. 251-62. PMID 9851857.Goodwin, E.B., P.G. Okkema, T.C. Evans, and J. Kimble, Translational regulation of tra-2 by its 3' untranslated region controls sexual identity in C. elegans. Cell, 1993. 75(2): p. 329-39. PMID 8402916.
- Kuwabara, P.E., P.G. Okkema, and J. Kimble, tra-2 encodes a membrane protein and may mediate cell communication in the Caenorhabditis elegans sex determination pathway. Mol Biol Cell, 1992. 3(4): p. 461-73. PMID 1498366.
- Okkema, P.G. and J. Kimble, Molecular analysis of tra-2, a sex determining gene in C.elegans. EMBO J, 1991. 10(1): p. 171-6. PMID 1703488.
- Rosenquist, T., J. Ahringer, M.K. Barton, P. Kuwabara, P. Okkema, and J. Kimble. (1990) Molecular genetics of sex determination in C. elegans. In "The 48th Symposium of the Society for Developmental Biology", A.P. Mahowald, ed., Alan R. Liss Inc., 91-102.
- Baker, S.M., P.G. Okkema, and J.A. Jaehning, Expression of the Saccharomyces cerevisiae GAL7 gene on autonomous plasmids. Mol Cell Biol, 1984. 4(10): p. 2062-71. PMID 6390184.